منابع مشابه
(α,α-dimethyl)glycyl (dmg) PNAs
The design and facile synthesis of sterically constrained new analogs of PNA having gem-dimethyl substitutions on glycine (dmg-PNA-T) is presented. The PNA oligomers [aminoethyl dimethylglycyl (aedmg) and aminopropyl dimethylglycyl (apdmg)] synthesized from the monomers 6 and 12) effected remarkable stabilization of homothyminePNA(2):homoadenine DNA/RNA triplexes and mixed base sequence duplexe...
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A review of data mining and analysis techniques that can be used for the mapping of knowledge domains is given. Literature mapping techniques can be based on authors, documents, journals, words, and/or indicators. Most mapping questions are related to research assessment or to the structure and dynamics of disciplines or networks. Several mapping techniques are demonstrated on a data set compri...
متن کاملContent Coverage of PNAS in 1982-2001
This paper reports results of determining changes in content coverage of the Proceedings of the National Academy of Science (PNAS). Dominant keywords were extracted to visualize major research topics and their evolution in the 20-year time frame. Two time slices namely 1995 and 2001 are examined in detail. Latent Semantic Analysis [6] was applied to determine the space of semantically similar d...
متن کاملReconceptualizing the classification of PNAS articles.
PNAS article classification is rooted in long-standing disciplinary divisions that do not necessarily reflect the structure of modern scientific research. We reevaluate that structure using latent pattern models from statistical machine learning, also known as mixed-membership models, that identify semantic structure in co-occurrence of words in the abstracts and references. Our findings sugges...
متن کاملMapping Topics and Topic Bursts in PNAS
Scientific research is highly dynamic. New areas of science continually evolve; others gain or lose importance, merge, or split. Due to the steady increase in the number of scientific publications, it is hard to keep an overview of the structure and dynamic development of one's own field of science, much less all scientific domains. However, knowledge of "hot" topics, emergent research frontier...
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ژورنال
عنوان ژورنال: Artificial DNA: PNA & XNA
سال: 2012
ISSN: 1949-095X,1949-0968
DOI: 10.4161/adna.19185